Is There Enough Evidence for the Association of GNβ3 C825T Polymorphism With Functional Dyspepsia and Irritable Bowel Syndrome?
نویسندگان
چکیده
منابع مشابه
Is There Enough Evidence for the Association of GNβ3 C825T Polymorphism With Functional Dyspepsia and Irritable Bowel Syndrome?
TO THE EDITOR: I read with great interest the paper from the Kim et al on the G-protein beta3 subunit (GNβ3) C825T polymorphism with overlap syndrome of functional dyspepsia (FD) and irritable bowel syndrome (IBS) which demonstrated that no apparent association of the GNβ3 C825T polymorphism with FD, IBS or the overlap of FD and IBS existed. However, a recent study on Korean children showed the...
متن کاملIs There Enough Evidence for the Association of GNβ3 C825T Polymorphism With Functional Dyspepsia and Irritable Bowel Syndrome?: Author's Reply
TO THE EDITOR: We appreciate the interest and comments on our paper, which was published in the July 2012 issue of this journal. We totally agree with the comment that many factors including heterogeneity of the disease, sample size, sample selection or racial difference may contribute to conflicting results of the genetic association studies in functional gastrointestinal disorders. Based on t...
متن کاملG-Protein Beta3 Subunit C825T Polymorphism in Patients With Overlap Syndrome of Functional Dyspepsia and Irritable Bowel Syndrome
BACKGROUND/AIMS Guanine nucleotide binding protein (G-protein) beta polypeptide 3 (GNB3) C825T polymorphism alters intracellular signal transduction, which may lead to motor or sensory abnormalities of the gastrointestinal tract. The aim of the present study was to evaluate the association of the GNB3 C825T polymorphism with susceptibility to overlap syndrome of functional dyspepsia (FD) and ir...
متن کاملIRRITABLE BOWEL SYNDROME Diagnostic yield of alarm features in irritable bowel syndrome and functional dyspepsia
Objective: The diagnostic value of the addition of alarm symptoms in distinguishing functional from organic gastrointestinal disease remains uncertain. We aimed to establish the value of alarm features in differentiating between organic disease and irritable bowel syndrome (IBS) and functional dyspepsia (FD). Methods: A total of 568 consecutive patients (63% female; mean age 44.7 years) complet...
متن کاملImpact of Shiftwork on Irritable Bowel Syndrome and Functional Dyspepsia
Disturbances in biological rhythms could lead to unfavorable health impact. This study aimed to evaluate the prevalence of functional dyspepsia (FD) and irritable bowel syndrome (IBS) in rotating shift workers, and to determine the factors that have significant association with the prevalence of FD and IBS. The research had been carried out among nurses and nursing assistants working at Ewha Wo...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Neurogastroenterology and Motility
سال: 2012
ISSN: 2093-0879,2093-0887
DOI: 10.5056/jnm.2012.18.3.348